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CLEVELAND -- Brandon Weeden never once hung his head after getting hurt and losing his job to a hometown hero. He figured the Browns would need him again, and he had to be ready. On Thursday night, his number was called and Weeden delivered. Weeden came off the bench after Brian Hoyer injured his knee and rallied the Browns to a 37-24 victory over the Buffalo Bills, who also lost starting rookie quarterback EJ Manuel with a knee injury. After spraining his right thumb in Week 2, Weeden watched as Hoyer, a lifelong Browns fan who began the season as Clevelands No. 3 quarterback, led the team to two straight wins. Weeden got healthy enough to play but found himself demoted to a backup role, not what the first-round draft pick imagined after being named the starter in training camp. He could have sulked or complained. Instead, he fought back. "Whether I was the starter, eyes are still on you to see how you respond, to see how you react," he said. "I was upbeat the entire time and never let it bother me. Inside, it just kind of lit a fire." Weeden threw a 37-yard touchdown pass to Josh Gordon in the third quarter as the Browns (3-2) won their third straight and temporarily moved into sole possession of first place in the AFC North. Its the Browns best record after five games since they were 3-2 in 2001. ""We dont care about history," Gordon said. "This is a new year and this is a new team." Safety T.J. Ward intercepted rookie Jeff Tuels pass and returned it 44 yards for a TD with 1:44 left to end any comeback hopes for the Bills (2-3). Travis Benjamin had an electrifying 79-yard TD punt return in the first half for Cleveland. Hoyer sustained a potentially serious right knee injury on a scramble in the first quarter, and Manuel was forced out after taking a helmet to his right knee on a run in the third. Neither returned and their injuries could impact both teams seasons. Following the game, Hoyer left the stadium on crutches with his knee immobilized. Browns coach Rob Chudzinski said Hoyer has a sprained knee and will undergo an MRI on Friday. But the tone of Hoyers teammates seemed to indicate that the 27-year-old, who was finally getting a chance to start in his fifth NFL season, might be sidelined for an extended period. "He was playing great, man," said Weeden, who added that Hoyer was in the locker room following the game to celebrate with his teammates. "You hate to see it because hes a teammate and a friend. I tried to be as positive with him as I could." With the Browns trailing 7-0, Hoyer took off on an 11-yard run and was sliding after picking up the first down when he was hit from the side by rookie linebacker Kiko Alonso. Both of Hoyers knees were bent awkwardly on the hit in front of Clevelands bench, and several players and coaches yelled for a penalty to be called on Alonso. Hoyer stayed on the ground for several moments before he was assisted to a trainers table. He limped to the locker room for tests and treatment. Hoyer was attempting to become the first quarterback in team history to win his first three starts -- now he may not get back on the field this season. "We definitely dont want to see a teammate go down like that, especially a guy like Hoyer," Gordon said. "Hes a great guy and I hope he comes back healthy." C.J. Spiller had a 54-yard TD run and Fred Jackson had a pair of 1-yard TD runs for the Bills, who could do nothing on offence once Manuel left. Manuel got hurt at the end of a 14-yard run when he was hammered near the sideline by Browns safety Tashaun Gipson. Manuel walked off the field attempted to get his knee loose on the sideline by jogging and riding a stationary bike. But after having his knee examined, he jogged to the locker room with two trainers. Bills coach Doug Marrone said the doctors told him Manuel has a sprained knee and assume he will have an MRI. "I was hoping we could get him back, but they said it was a sprain and they shut him down," Marrone said. "Hes a tough kid. He took a shot. He was trying to score a touchdown." Billy Cundiff kicked field goals of 24 and 44 yards in the fourth quarter for the Browns, who overcame a 10-0 deficit and were down 24-17 less than two minutes into the second quarter. Cundiffs second kick with 2:91 left put the Browns ahead 30-24, and Cleveland turned it over to their third-ranked overall defence. Beyond the quarterbacks, both teams had one other key player go down with an injury. Bills leading receiver Stevie Johnson injured his back in the first half and didnt return. Johnson caught two catches for 19 yards before he went out. Browns defensive end Desmond Bryant was taken to the Cleveland Clinic in the third quarter after experiencing shortness of breath. Last year with Oakland, Bryant had to be hospitalized during a game with an irregular heartbeat, but returned to play the next week With Buffalo leading 24-17, Weeden found Gordon down the left sideline and the wide receiver made a juggling catch. Weeden started slowly but finished 13 of 24 for 197 yards. "He did a great job," tight end Jordan Cameron said. "At first he was a little rusty. I think he shook that off and really got us going." NOTES: Benjamin set a team record with 179 return yards, breaking the mark held by Eric Metcalf, who had 166 on Oct. 24, 1993, against Pittsburgh. ... Bills DE Mario Williams had two sacks, moving him into a tie for the league lead with 7 1/2. ... Bills WR T.J. Graham sustained a neck injury in the fourth but returned. ... Browns RB Chris Ogbonnaya left in the first half with a concussion and did not return. ... With three catches, Cameron has 33 this season, the most by a Browns TE in the first five games. Nike NFL Jerseys Outlet . 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CHAUNCEY BILLUPS (Pistons): Yes they got Josh Smith and Brandon Jennings in the off-season and Andre Drummond is a beast (teams are kicking themselves for passing on him - he rebounds and block shots every game - thats two more discernable and significant skills than most guys in his draft class), but dont for a second discount the impact of having a savvy veteran like Billups on your team. Nike NFL Jerseys Cheap . The alley-oop looked easy -- just like everything else after halftime for the Miami Heat. James scored 32 points, Wade added 22 points and eight assists, and the Heat trailed by 11 early in the second half before running away to a 107-88 victory over the New Orleans Pelicans on Tuesday night.BUFFALO, N.Y. -- A fast start, a few opportune bounces and rookie goalie Dustin Tokarskis shutout performance allowed the Montreal Canadiens to avoid needing any late-game dramatics on consecutive nights. A day after being called up from AHL Hamilton, Tokarski made 29 saves to earn his first career shutout in a 2-0 win over the injury-depleted Buffalo Sabres on Sunday night. "It felt pretty good. Im not going to lie," Tokarski said. "The main thing is the two points going down the stretch here for this hockey team, and just a little icing on the cake with the shutout, I guess." The shutout was certainly timely for a Canadiens team coming off an emotional high following a 5-4 overtime win over the Ottawa Senators on Saturday night. It was a game in which Montreal became the NHLs first team to win by overcoming a three-goal deficit with less than five minutes remaining. "Every time you play an emotional game, as a coach youre always afraid that the next game could be tougher," coach Michel Therrien said. "But we got a really good start, and this is something weve been doing lately." Brendan Gallagher and Dale Weise scored 1:26 apart in the first period, both coming off pucks that caromed into the net. Weise opened the scoring when a rebound banked in off his skate. Gallaghers goal came on a rebound that caromed in off the leg of Sabres defenceman Chad Ruhwedel. Montreal (37-25-7) vaulted into second place in the Atlantic Division by jumping ahead of Toronto and Tampa Bay. The league-worst Sabres (19-41-8) continue heading in reverse, having lost six straight in regulation -- their worst streak since losing seven in a row from Dec. 4-19, 2003. And theyve lost another goalie to injury after starter Jhonas Enroth did not return following a collision with Gallagher with 3:51 left in the second period. Referring to it as a lower-body injury, coach Ted Nolan said Enroth could be out indefinitely. "It doesnt look like its going to be short-term," Nolan said. "It seems like we have bad luck, or we have no luck at all." Gallagher was driving to the net from the left circle and got a shot off when he was struck from behind by Buffalo defenceman Jamie McBain and tumbled directly into Enroth. The goalie lay on thhe ice for a few minutes before he got up and attempted to stretch his right leg while being examined by a trainer.dddddddddddd Enroth then skated to the bench and was escorted into the locker room. Rookie Nathan Lieuwen was forced into action, and stopped all 10 shots he faced in his NHL debut. Lieuwen was called up from AHL Rochester earlier in the day after backup Michal Neuvirth complained of a lower body injury before Buffalos 4-1 loss at the New York Islanders on Saturday. That leaves the Sabres in a position of calling up Matt Hackett from Rochester before embarking on a five-game road trip that opens at Calgary on Tuesday. Lieuwen was playing on his third consecutive day after stopping 31 shots in a 2-1 overtime loss to Binghamton on Friday, and another 38 in a 2-1 loss to Binghamton on Saturday. "It was all adrenaline," Lieuwen said. "How I played the two nights before really did help. As soon as the faceoff started, it was like I was in a game again, and I could focus in." His best save came with 10:25 left, when he lunged from his crease and got his blocker up to turn aside former Sabres player Thomas Vaneks one-timer from the slot. Tokarski started in place of Carey Price, who didnt travel with the team. Therrien was wary of playing Price on consecutive nights after the goalie aggravated a lower-body injury during Canadas gold-medal run at the Sochi Games. Tokarski was sharp in the opening frame, when he turned aside Drew Staffords backhander in front. He was also fortunate with 12:47 left in the third period, when Stafford had a shot go off the right post. The Sabres continue to struggle generating offence. Theyve managed a league-worst 132 this season, and have scored just five in their past six games. NOTES: Vanek played his first game at Buffalo since the Sabres traded him to the New York Islanders in October. The Canadiens acquired Vanek in a deal with the Isles two weeks ago. Vanek drew a standing ovation during a first-period break, after the Sabres broadcast a series of highlights on their videoboard. ... Buffalo will close the season playing 10 of its final 14 games on the road. ... Nolan expects C Torrey Mitchell to be ready to return Tuesday, after missing his sixth game with a lower body injury. ' ' '